DISCOVERY products for advanced IHC and ISH tissue research

Breaking barriers to advance science


slanted slides for IHC resources

Build the future with a solution developed for researchers, by researchers

Bringing flexible capabilities to support tissue research and development of diagnostics, Roche’s DISCOVERY staining platform provides a solution for scientists and research professionals who demand more than what conventional immunohistochemistry (IHC) and in situ hybridization (ISH) platforms have to offer.

The key components of the DISCOVERY tissue research solution are:

  • DISCOVERY ULTRA instrument: Automated multiplex IHC/ISH staining
  • Universal Software: Enables the flexibility to design sophisticated multiplexing protocols on the DISCOVERY ULTRA
  • Reagents: A wide range of ready to use antibodies, flexible detection chemistries for low abundance targets, tyramide-deposited fluorophores and next-generation chromogens to support diverse IHC and ISH staining applications

The DISCOVERY ULTRA is an open platform allowing access to third-party or custom reagents via user-fillable dispensers and the Universal Software. 

Featured products

The DISCOVERY ULTRA research instrument is the solution for scientists and research professionals who demand more than what conventional immunohistochemistry (IHC) and in situ hybridization (ISH) research methods have to offer. The DISCOVERY ULTRA research instrument offers our highest level of protocol flexibility for the most challenging assays and for rapid assay development. The thirty independent slide drawers allow for titration capability for each individual slide. This instrument offers enhanced multiplexing and immunofluorescence capabilities. It also saves valuable development time with continuous access to bulks, waste and reagents.

Learn more about DISCOVERY products for advanced IHC and ISH tissue research

Immunohistochemistry (IHC)

Flexible Immunohistochemistry (IHC) capabilities to support research and development of cancer diagnostics

Immunohistochemistry (IHC) is used to diagnose disease, measure response to therapeutic drugs, and research countless basic biological applications. It is an essential tool for cancer research and diagnostics.

Learn more about immunohistochemistry, and how the Ventana DISCOVERY ULTRA its advanced reagents can help you accomplish your research goals.

Chromogenic staining

Next-generation VENTANA chromogens enable advanced multiplexed IHC and ISH staining ideal for computational pathology image analysis

The Research and Development team at VENTANA have developed several new chromogens and fluorophores to expand IHC and ISH multiplexing and assay development.  These distinctive chromogens achieve strong, high-quality staining and have robust stability in ethanol and xylene.  These reagents are in stable ready-to-use dispensers with no mixing required.  When combined with our flexible selection of multimer, hapten and amplification detection chemistries, they can easily be tuned to the unique sensitivity needed for each of your biomarker targets.

Learn more about advanced Ventana chromogens, how they work, and how they can help you accomplish your IHC and ISH research goals.

IHC multiplexing

Multiplexed IHC enables investigators to gain unique biological insights not possible with single stains

What is Multiplexed Immunohistochemistry?

Multiplexed immunohistochemistry (mIHC) enables the detection of multiple biomarker antigens on the same tissue section. Compared to single stains, simultaneous biomarker detection enables a greater understanding of the tissue.

Whether you are just getting started with mIHC or you are experienced with mIHC, mISH or same-slide IHC plus ISH multiplexing, you can find extensive theory, advice, protocols and other helpful information within our Multiplexing Resources

DISCOVERY ULTRA

Build the future with the DISCOVERY ULTRA

Powered by flexible software, the DISCOVERY ULTRA leads the way in capabilities for mIHC, mISH or same-slide IHC plus ISH multiplexing, for R&D environments in leading Pharmaceutical Companies, Contract Research Organizations (CRO), and Academic Medical Centers.

Educational resources

Educational Resources for immunohistochemistry and in situ hybridization

Explore our Educational Resources:

  • Roche Diagnostics University
  • Peer-reviewed publication for the DISCOVERY ULTRA
  • Video Library
  • White papers
  • FAQs
  • DISCOVERY product catalog

Contact Roche

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