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cobas e 411 analyzer

cobas e 411 analyzer for immunoassay tests (disk system)

The cobas e 411 analyzer is a fully automated analyzer that uses a patented ElectroChemiLuminescence (ECL) technology for immunoassay analysis. It is designed for both quantitative and qualitative in vitro assay determinations for a broad range of applications (including anemia; bone, cardiac and tumor markers; critical care; fertility/hormones; and infectious diseases). The analyzer is available as a rack or disk sample handling system.

cobas e 411 analyzer for immunoassay tests (rack system)

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First class performance

High sensitivity, reliability, and reproducibility of results due to ECL technology
More than 100 assays available¹
Up to 18 assays can be run at a throughput of up to 86 tests/h²
9 min STAT applications for emergency sample assays (incl. TnT Gen. 5, Creatine-Kinase MB, Myoglobin, Parathyroid Hormone (PTH), and human Chorionic Gonadotropin (hCG)¹

Intelligent sample workflow

Carryover-free pipetting of samples to avoid cross-contamination
Automated sample rerun capability
Continuous random access and flexible STAT priority settings
The use of disposable tips for all sample pipetting delivers carryover free pipetting to avoid cross-contamination

Unique reagent concept

Convenient and error-free handling of cobas e packs
Economic usage with high stabilities and convenient kit sizes

High system reliability

More than 25,000 analyzers installed worldwide³
High uptime of 98.6%⁴
Low system maintenance time

cobas^® 4000 analyzer series

Freedom to realize your lab’s potential

The cobas^® 4000 analyzer series consists of the cobas c 311 analyzer for clinical chemistry and the cobas e 411 analyzer for immunochemistry testing.

References

Elecsys^® Assay menu. Roche Diagnostics International Ltd.
cobas e 411 analyzer. Operator's manual. Roche Diagnostics International Ltd.
Data on file. Roche Diagnostics International Ltd.
Data on file. Roche Diagnostics International Ltd.

cobas c 411 analyzer

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System	Fully automated, immunoassay analyzer for random access processing of ECL-based immunoassays (cobas e system format)
System components	Self contained bench top analyzer comprising an analytical unit and a customized user interface
Types of modules	cobas e 411 disk analyzer cobas e 411 rack analyzer Optional System Table (cabinet); Optional System Table Extension (for printer)
System interfaces	RS232 serial interface, bidirectional
Throughput	Up to 86 tests/hour
Number of reagent channels	25 reagent slots with a maximum of 18 on-board assays
Programmable test parameters	N/A, programming-by-loading (PBT) concept, application data are transferred without operator intervention from the 2D barcode of the reagent pack (RP) into the instrument database
Sample materials	Serum/plasma, urine, others
Sample input/output	30 positions for samples, calibrators and controls 15 racks with 5 samples each (= 75 samples in/out)
Sample volume	10 - 50 μl.
Sample clot detection	Standard (pressure sensor)
Sample barcode types	Code 128; Codabar (NW 7); Interleaved 2 of 5; Code 39
Control unit	Microsoft® Windows® XP-based panel PC
Calibrator/QC input	cobas e system-specific barcoded CalSet vials on disk or racks
Calibration methods	Lot calibration (L-cal); Reagent Pack (RP) calibration (R-Cal)
QC methods	Individual QC and cumulative QC Up to 100 controls pre-programmable
Data storage capacity	The memory contains data files necessary for the analyzer and software to work together: Reagent Data File: Up to 300 reagent packs Sample Data File: Up to 2000 test records (for samples and controls) Calibration Data File: Up to 160 calibrators - QC Data File: Capacity up to 100 controls Operating Parameter Data File: Up to 305 reagent applications Up to 20 operator IDs
Electrical requirements	230/110 Volts AC; 1,000 kVA (disk), 1,250 kVA (rack) Frequency: 50 Hz or 60 Hz +/- 0.5%
Water/Waste requirements	Water: Bacteria free, de-ionized water supply, resistance of less than 10 μS/cm Liquid waste: Onboard waste container (4 liter), direct drain optional
Operating conditions	Ambient temperature: 18 to 32°C Ambient humidity: 20 to 80% RH (without condensation) Heat Output: 2,879 kJ/hr (analyzer unit) Noise Output: 60 dBA (stand-by), 63 dBA (operation avg.)
Physical dimensions	Width (disk/rack): 120 cm / 170 cm 47.2 in / 67 in Depth (disk/rack): 73 cm / 95 cm 28.7 in / 37.4 in Height: 80 cm / 31.4 in (closed top cover) 109 cm / 43 in (opened top cover)
Weight	Disk: 180 kg / 397 lbs Rack: 250 kg / 551 lbs