cobas e 411 analyzer

cobas e 411 analyzer
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First class performance

  • High sensitivity, reliability, and reproducibility of results due to ECL technology 
  • More than 100 assays available1 
  • Up to 18 assays can be run at a throughput of up to 86 tests/h2
  • 9 min STAT applications for emergency sample assays (incl. TnT Gen. 5, Creatine-Kinase MB, Myoglobin, Parathyroid Hormone (PTH), and human Chorionic Gonadotropin (hCG)1


Intelligent sample workflow 


  • Carryover-free pipetting of samples to avoid cross-contamination 
  • Automated sample rerun capability
  • Continuous random access and flexible STAT priority settings
  • The use of disposable tips for all sample pipetting delivers carryover free pipetting to avoid cross-contamination


Unique reagent concept


  • Convenient and error-free handling of cobas e packs
  • Economic usage with high stabilities and convenient kit sizes


High system reliability


  • More than 25,000 analyzers installed worldwide
  • High uptime of 98.6%4
  • Low system maintenance time


cobas e 411
Product image for cobas® 4000 analyzer series

cobas® 4000 analyzer series

Freedom to realize your lab’s potential

The cobas® 4000 analyzer series consists of the cobas c 311 analyzer for clinical chemistry and the cobas e 411 analyzer for immunochemistry testing.



  1. Elecsys® Assay menu. Roche Diagnostics International Ltd.
  2. cobas e 411 analyzer. Operator's manual. Roche Diagnostics International Ltd.
  3. Data on file. Roche Diagnostics International Ltd.
  4. Data on file. Roche Diagnostics International Ltd.

cobas c 411 analyzer

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cobas c 411 analyzer

System Fully automated, immunoassay analyzer for random access processing of ECL-based immunoassays (cobas e system format)
System components Self contained bench top analyzer comprising an analytical unit and a customized user interface
Types of modules
  • cobas e 411 disk analyzer
  • cobas e 411 rack analyzer
  • Optional System Table (cabinet); Optional System Table Extension (for printer)
System interfaces RS232 serial interface, bidirectional
Throughput Up to 86 tests/hour
Number of reagent channels 25 reagent slots with a maximum of 18 on-board assays
Programmable test parameters N/A, programming-by-loading (PBT) concept, application data are transferred without operator intervention from the 2D barcode of the reagent pack (RP) into the instrument database
Sample materials Serum/plasma, urine, others
Sample input/output
  • 30 positions for samples, calibrators and controls
  • 15 racks with 5 samples each (= 75 samples in/out)
Sample volume 10 - 50 μl.
Sample clot detection Standard (pressure sensor)
Sample barcode types Code 128; Codabar (NW 7); Interleaved 2 of 5; Code 39
Control unit Microsoft® Windows® XP-based panel PC
Calibrator/QC input cobas e system-specific barcoded CalSet vials on disk or racks
Calibration methods Lot calibration (L-cal); Reagent Pack (RP) calibration (R-Cal)
QC methods
  • Individual QC and cumulative QC
  • Up to 100 controls pre-programmable
Data storage capacity The memory contains data files necessary for the analyzer and software to work together:
  • Reagent Data File: Up to 300 reagent packs
  • Sample Data File: Up to 2000 test records (for samples and controls)
  • Calibration Data File: Up to 160 calibrators - QC Data File: Capacity up to 100 controls
  • Operating Parameter Data File: Up to 305 reagent applications
  • Up to 20 operator IDs
Electrical requirements
  • 230/110 Volts AC; 1,000 kVA (disk), 1,250 kVA (rack)
  • Frequency: 50 Hz or 60 Hz +/- 0.5%
Water/Waste requirements
  • Water: Bacteria free, de-ionized water supply, resistance of less than 10 μS/cm
  • Liquid waste: Onboard waste container (4 liter), direct drain optional
Operating conditions
  • Ambient temperature: 18 to 32°C
  • Ambient humidity: 20 to 80% RH (without condensation)
  • Heat Output: 2,879 kJ/hr (analyzer unit)
  • Noise Output: 60 dBA (stand-by), 63 dBA (operation avg.)
Physical dimensions
  • Width (disk/rack): 120 cm / 170 cm 47.2 in / 67 in
  • Depth (disk/rack): 73 cm / 95 cm 28.7 in / 37.4 in
  • Height: 80 cm / 31.4 in (closed top cover) 109 cm / 43 in (opened top cover)
  • Disk: 180 kg / 397 lbs
  • Rack: 250 kg / 551 lbs