Elecsys® AMH (Anti-Mullerian Hormone)

Elecsys® AMH (Anti-Mullerian Hormone)

Providing clinical confidence in reliable ­assessment of ovarian reserve

Mean female age at first birth has increased steadily over the past few decades in many developed countries. This postponement leads to couples attempting to have children during a period where female fertility is already in decline.

 

Anti-Müllerian hormone (AMH)

 

AMH is a direct serum marker of functional ovarian reserve and plays an important role in assessing ovarian reserve levels.1,2

Serum AMH levels have been shown to remain relatively stable during the menstrual cycle and may be measured on any day of the cycle.1,2

AMH is a reliable marker for the assessment of the ovarian reserve in conjunction with other clinical and laboratory findings before starting any fertility therapy. AMH adds prognostic information to the counseling and planning process for infertile couples seeking fertility treatment.

 

  • Fully automated, fast, sensitive and robust measurement of AMH3
  • High precision over entire measuring range for reliable results3
  • Clinical agreement with Antral-Follicle-Count (AFC)4
  • Age specific reference ranges.
Elecsys® AMH (Anti-Mullerian Hormone)

Elecsys® AMH (Anti-Mullerian Hormone)

  • Assay time

    18 min

  • Sample material

    Serum and Li-heparin plasma

  • Sample volume

    50 µL

  • Measuring range

    0.03-23 ng/mL

  • Imprecision

    <5%

  • LoB, LoD, LoQ

    0.007 ng/mL, 0.010 ng/mL, 0.030 ng/mL

  • Repeatability

    (cobas e411) 1.0-1.6% (0.055-19.0 ng/mL)

  • Intermediate Precision

    (cobas e 411) 1.2-2.3% (0.055-19.0 ng/mL)

References

 

  1. Van Disseldorp, J. et al. (2010). Hum Reprod; 25:221–227.
  2. Tsepelidis, S. et al. (2007). Hum Reprod; 22:1837–1840.
  3. Anti-Müllerian Hormone. Elecsys and cobas e analyzers package insert 2016.
  4. Anderson, R.A., Anckaert, E., Bosch, E. et al. (2015). Fertil Steril; 103(4):1074–1080.e4.