For Research Use Only (RUO)
Influenza virus, primarily type A and type B, is responsible for human epidemics causing worldwide morbidity and mortality.1 Respiratory syncytial virus is a leading cause of lower respiratory tract infections and hospitalizations in infants and children,2 and is associated with a substantial disease and health economic burden in older adults.3
The cobas® Influenza A/B & RSV UC Test for use with the cobas omni Utility Channel on the high-throughput cobas® 6800/8800 Systems and is a multiplex assay for the qualitative detection and differentiation of respiratory viruses Influenza A, Influenza B and RSV.
Centers of Disease Control and Prevention. Understanding Influenza Viruses. https://www.cdc.gov/flu/about/viruses/index.htm. Accessed 15 June 2021.
Smith DK, Seales S, Budzik C. Respiratory Syncytial Virus Bronchiolitis in Children. Am Fam Physician. 2017;95(2):94-99.
Ackerson B, Tseng HF, Sy LS, et al. Severe Morbidity and Mortality Associated With Respiratory Syncytial Virus Versus Influenza Infection in Hospitalized Older Adults. Clin Infect Dis. 2019;69(2):197-203. doi:10.1093/cid/ciy991.
Test performanceView Full Table
|Test results||Agreement Statistics|
|Virus||Number of Samples||Concordant Positive (N)||Discordant Positive (N)||Concordant Negative (N)||Discordant Negative (N)||Agreement Parameter||Percent Agreement (%)||95% CI (LCL, UCL)*|
|Influenza A||377||91||6||280||0||PPA||100.0%||(95.9%, 100.0%)|
|Inluenza B||377||85||4||287||1||PPA||98.8%||(93.7%, 99.8%)|
Key ParametersView Full Table
|Targets||Influenza A, influenza B, respiratory syncytial virus|
|Sample and media types||Nasopharyngeal swab samples collected in the Copan UTM-RT® System, the BD™ UVT System or equivalent|
|Minimum amount of sample required||0.6 mL|
|Sample processing volume||0.4 mL|
|Test duration||Results are available within less than 3.5 hours after loading the sample on the system|
|System software||cobas® 6800/8800 System Software 1.4 or higher|