To view associated reagents, ancillaries and bulks, please visit the Roche Tissue Diagnostics reagent catalog.
CINtec PLUS Cytology is powered by dual-stain biomarker technology that detects the simultaneous presence within a single cell of two biomarkers: p16 & ki67. The co-expression of the two biomarkers provide a strong indicator of the presence of a transforming HPV infection and that a woman may be at a higher risk for cervical disease.
CINtec PLUS Cytology is performed from the same ThinPrep sample as HPV and Pap tests, and run on the BenchMark ULTRA platform.
CINtec PLUS Cytology Intended Uses:
*For HPV16/18+ use as additional information in conjunction with the physician's assessment of patient screening history, other risk factors, and professional guidelines to guide patient management.
Results from the CINtec PLUS Cytology test should be interpreted by a qualified pathologist.
*For HPV16/18+ use as additional information in conjunction with the physician's assessment of patient screening history, other risk factors, and professional guidelines to guide patient management.
Results from the CINtec PLUS Cytology test should be interpreted by a qualified pathologist.
CINtec PLUS Cytology is run on the BenchMark ULTRA. The BenchMark ULTRA system is a fully automated immunohistochemistry and in situ hybridization slide staining system, offering multiple features designed to provide diagnostic confidence to histopathology laboratories worldwide. With 30 independent slide drawers, the system gives histotechnologists continuous random access and supports single-piece workflow, which numerous studies have shown improves laboratory operational efficiency.
The following publications provide further evidence of the clinical utility of p16/Ki-67 dual staining in cervical cancer screening: