For in vitro diagnostic use. Nucleus Cytoplasm Others anti-ALK1 ALK01 CONFIRM IVD Anaplastic Large Cell Lymphoma CONFIRM anti-ALK1 (ALK01) Primary Antibody RTD000763 US-FDA Mouse ALK01 790-2918 CONFIRM anti-ALK1 (ALK01) Primary Antibody 04015630970063 50 tests true CONFIRM anti-ALK1 (ALK01) 05278147001 Not Available Reagents, kits en This antibody is intended for in vitro diagnostic (IVD) use.Ventana Medical Systems’ (Ventana) CONFIRM anti-ALK1 (ALK01) Primary Antibody is a mouse monoclonal antibody directed against p80 protein present in human tissue. This antibody is intended for laboratory use to qualitatively stain sections of formalin fixed, paraffin embedded tissue on a Ventana automated slide stainer.The clinical interpretation of any staining, or the absence of staining, must be complemented by morphological studies and evaluation of proper controls. Evaluation must be made by a qualified pathologist within the context of the patient’s clinical history and other diagnostic tests. Prescription only. en CONFIRM anti-ALK1 (ALK01) may be used as the primary antibody for immunohistochemical staining of paraffin tissue sections. In general, immunohistochemical staining allows the visualization of antigens via the sequential application of a specific antibody (primaryantibody) to the antigen, a secondary antibody (link antibody) to the primary antibody, anenzyme complex and a chromogenic substrate with interposed washing steps. The enzymatic activation of the chromogen results in a visible reaction product atthe antigen site. The specimen may then be counterstained and cover slipped. Results are interpreted using alight microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen.CONFIRM anti-ALK1 (ALK01) is optimally diluted for use with Ventana detection kits and automated slide stainers. Each step in thestaining protocol includes incubation for a precise time at a specific temperature. Atthe end of each incubation step, the sections are rinsed by the Ventana automated slide stainer to stop the reaction and remove unbound material that would hinder the desired reaction in subsequent steps. To minimize evaporation of the aqueous reagents from the specimen containing slide a coverslip solution is applied in the slide stainer. Staining is completed after incubation with a substrate chromogen and optional counterstaining. For more detailed information on instrument operation, refer to the appropriate Ventana automated slide stainer Operator's Manual.