For in vitro diagnostic use. Others CINtec Histology Kit IVD Normal Pancreas Normal Tonsil Cervical Carcinoma CINtec® Histology Kit RTD000755 Japan Mouse E6H4™ 06 594 450 001 6 594 450 001 06594450001 6594450001 06594450001 CINtec Histology Kit (Class 1) CINtec Histology Kit 07613336171103 Reagents, kits 9517 50 tests Not Available false The CINtec® Histology Kit is an immunohistochemistry assay for the qualitative detection of the p16INK4a antigen on formalin-fixed, paraffin-embedded tissue sections prepared from cervical biopsies. It is intended for use in medical pathology laboratories to provide adjunctive information after initial diagnosis has been made by established diagnostic methods. Interpretation of the test results may only be made by a certified professional in conjunction with the patient ́s clinical history and any additional diagnostic tests that have been performed. en The CINtec® Histology Kit contains a set of reagents for the immunohistochemical detection of the p16INK4a antigen. The Kit is designed to perform a two-step immunohistochemical staining procedure for formalin-fixed, paraffin-embedded tissue specimens obtained from cervical biopsies. For the detection of the antigen, a primary monoclonal mouse antibody clone E6H4™ directed to human p16INK4a protein is used.A ready-to-use visualization reagent comprising a polymer reagent conjugated with horseradish peroxidase and goat anti-mouse Fab’ antibody fragments is used. The Visualization Reagent has been subjected to solid-phase absorption to eliminate cross reactivity with human immunoglobulins. The chromogen reaction is based on horseradish peroxidase-mediated conversion of a DAB chromogen to a visible reaction product at the antigen site. After counterstaining, the specimen may be cover-slipped and the results may be evaluated by light microscopy inspection. en

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