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Do not freeze.", "Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Intended Use", "Value": "IgG Rabbit Polyclonal Primary Antibody is intended for laboratory use in the detection of IgG in formalin-fixed, paraffin-embedded tissue stained on VENTANA BenchMark IHC/ISH instruments. This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls. This antibody is intended for in vitro diagnostic (IVD) use.", "Language": "en", "Country": "XG", "Code": "Intended Use" }, { "Name": "Content", "Value": "One dispenser of this antibody contains sufficient prediluted reagent for 50 tests.", "Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Background Information", "Value": "Anti-IgG reacts with immunoglobulin gamma (IgG) chains. This antibody is useful when differentiating and sub-classifying hematolymphoid neoplasms.1-5

1. Arnold A, et al. Immunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasms. New Eng J Med. 1983; 309:1593-9.
2. Leong AS, et al. Manual of Diagnostic Antibodies for Immunohistology. Greenwich Medical Media Ltd. 1999. London. pp 217-9. Print.
3. Ando K, et al. IgA-lambda/IgG-kappa biclonal myeloma in which two clones proliferated in individual sites. Intern Med. 2000; 39:170-5.
4. Taylor CR, et al. Immunoperoxidase techniques: practical and theoretical aspects. Arch Path Lab Med. 1978; 102:113-21.
5. Warnke R, et al. Tissue section immunologic methods in lymphomas. In: Diagnostic Immunohistochemistry. Edited by R DeLellis. Masson Publishing, 1981. New York. pp 203-21. Print.", "Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Principle", "Value": "IgG Rabbit Polyclonal Antibody (this antibody) may be used as the primary antibody for immunohistochemical staining of formalin-fixed, paraffin-embedded tissue sections. In general, immunohistochemical staining allows the visualization of antigens via the sequential application of a specific antibody (primary antibody) to the antigen, a secondary antibody (link antibody) to the primary antibody, an enzyme complex and a chromogenic substrate with interposed washing steps. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and a coverslip applied. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen.

This antibody is optimally diluted to be compatible with VENTANA detection kits and BenchMark IHC/ISH instruments. Refer to the Tables in the Instructions for Use section for recommended staining protocols. Each step in the staining protocol includes incubation for a precise time at a specific temperature. At the end of each incubation step, the sections are rinsed by the BenchMark IHC/ISH instruments to stop the reaction and remove unbound material that would hinder the desired reaction in subsequent steps. To minimize evaporation of the aqueous reagents from the specimen-containing slide, a coverslip solution is applied in the slide stainer. For more detailed information on instrument operation, refer to the appropriate BenchMark IHC/ISH instruments Operator’s Manual.", "Language": "en", "Country": "XG", "Code": "Principle" }, { "Name": "Product Purpose", "Value": "IgG Rabbit Polyclonal Primary Antibody is intended for laboratory use in the detection of IgG in formalin-fixed, paraffin-embedded tissue stained on VENTANA BenchMark IHC/ISH instruments. This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls. This antibody is intended for in vitro diagnostic (IVD) use.", "Language": "en", "Country": "XG", "Code": "Product Purpose" } ] } } ] }

IgG Rabbit Polyclonal Antibody

IVD For in vitro diagnostic use.
IgG Rabbit Polyclonal Antibody

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