For in vitro diagnostic use. Others Jones Staining Kit IVD Kidney Jones Staining Kit RTD001010 05279348001 Jones Staining Kit Jones H&E Staining Kit 04015630971626 Reagents, kits 860-019 40 tests Not Available true The Jones Staining Kit is intended for laboratory use as a qualitative histologic stain to demonstrate capillary basement membranes by light microscopy in sections of formalin-fixed, paraffinembedded (FFPE) tissue stained on the BenchMark Special Stains instrument.This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls.This product is intended for in vitro diagnostic (IVD) use. en The staining reaction is based on aldehyde reduction of silver ions to metallic silver under alkaline conditions. Jones Periodic Acid is used to oxidize carbohydrates to aldehyde groups. The combined Jones Silver A and Jones Silver B solutions form a methenaminesilver complex that is easily reduced to metallic silver by the aldehyde groups. To enhance staining contrast, toning of tissue specimen is completed using gold chloride within the Toner reagent. Fixer, with thiosulfate, stops the reaction and removes any unreduced silver from the section.5,8 Nuclei are stained with Jones Hematoxylin and Jones Eosin is applied to provide a contrasting background.This kit is optimized for use on BenchMark Special Stains instruments. The reagents are applied to tissue on microscope slides and mixed over the entire specimen.5. Bancroft JD, Layton C. Connective and Other Mesenchymal Tissues with TheirStains. In: Bancroft's Theory and Practice of Histological Techniques.2019:153-175.8. Jones DB. Nephrotic Glomerulonephritis. Am J Pathol. 1957;33(2):313-329. en