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(Product)", "Value": "Upon receipt and when not in use, store at 2-8°C. Do not freeze.", "Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Intended Use", "Value": "Lysozyme Rabbit Polyclonal Primary Antibody is intended for laboratory use in the detection of lysozyme in formalin-fixed, paraffin-embedded tissue stained on VENTANA BenchMark IHC/ISH instruments. This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls. This antibody is intended for in vitro diagnostic (IVD) use.", "Language": "en", "Country": "XG", "Code": "Intended Use" }, { "Name": "Content", "Value": "One dispenser of this antibody contains sufficient prediluted reagent for 50 tests.", "Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Background Information", "Value": "Immunohistochemical study with Lysozyme has been shown to have cytoplasmic expression in hematopoietic cells and non-hematopoietic cells, like renal proximal convoluted tubules.1 Lysozyme may be used as a non-specific marker of tissue macrophages (such as alveolar macrophages and liver Kupffer cells), histiocytes, monocytes, myeloid cells, and their proliferations and neoplasms.1 Anti-lysozyme may aid in the identification of histiocytic lesions and neoplasias, acute myelomonocytic leukemia, acute monocytic leukemia and Langerhans cell histiocytosis.2

1. Rehg J, et al. The utility of immunohistochemistry for the identification of hematopoietic and lymphoid cells in normal tissues and interpretation of proliferative and inflammatory lesions of mice and rats. Toxicol Pathol. 2012; 40: 345-74.
2. Seifert RP, et al. A practical approach to diagnose soft tissue myeloid sarcoma preceding or coinciding with acute myeloid leukemia. Annals Diag Pathol. 2014; 18:253-60.", "Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Principle", "Value": "Lysozyme Rabbit Polyclonal Antibody (this antibody) may be used as the primary antibody\nfor immunohistochemical staining of formalin-fixed, paraffin-embedded tissue sections. In\ngeneral, immunohistochemical staining allows the visualization of antigens via the sequential\napplication of a specific antibody (primary antibody) to the antigen, a secondary antibody\n(link antibody) to the primary antibody, an enzyme complex and a chromogenic substrate\nwith interposed washing steps. The enzymatic activation of the chromogen results in a visible\nreaction product at the antigen site. The specimen may then be counterstained and a coverslip\napplied. Results are interpreted using a light microscope and aid in the differential diagnosis\nof pathophysiological processes, which may or may not be associated with a particular\nantigen.\n
\n
\nThis antibody is optimally diluted to be compatible with VENTANA detection kits and\nBenchMark IHC/ISH instruments. Refer to the Tables in the Instructions for Use section for\nrecommended staining protocols. Each step in the staining protocol includes incubation for\na precise time at a specific temperature. At the end of each incubation step, the sections are\nrinsed by the BenchMark IHC/ISH instruments to stop the reaction and remove unbound\nmaterial that would hinder the desired reaction in subsequent steps. To minimize evaporation\nof the aqueous reagents from the specimen-containing slide, a coverslip solution is applied\nin the slide stainer. For more detailed information on instrument operation, refer to the\nappropriate BenchMark IHC/ISH instruments Operator’s Manual.", "Language": "en", "Country": "XG", "Code": "Principle" }, { "Name": "Product Purpose", "Value": "Lysozyme Rabbit Polyclonal Primary Antibody is intended for laboratory use in the detection of lysozyme in formalin-fixed, paraffin-embedded tissue stained on VENTANA BenchMark IHC/ISH instruments. This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls. This antibody is intended for in vitro diagnostic (IVD) use.", "Language": "en", "Country": "XG", "Code": "Product Purpose" } ] } } ] }

Lysozyme Rabbit Polyclonal Antibody

IVD For in vitro diagnostic use.
Lysozyme Rabbit Polyclonal Antibody

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