Roche Cell-Free DNA Collection Tube (RUO)

• Safety and durability through polyethylene terephthalate (PET) material
• Manufactured in accordance with ISO 9001 and EN ISO 13485
• Easy-to-handle plastic tubes to reduce potential breakage, injuries, and cost

• Prevention of blood coagulation with K3EDTA
• Preservation of nucleated cells and cfDNA
• Better stability across transit and different temperatures***

Figure 1: The Roche Cell-Free DNA Collection Tubes show comparable stability across 7 days of transit from samples collected for a noninvasive prenatal testing (NIPT) assay.

Cell lysis decreases minor cfDNA fraction. Average and standard deviations of minor cell-free DNA fraction measured from 66,000 samples collected and stored using Roche Cell-Free DNA Collection Tubes compared to another product in the market across a 7-day period in ambient transit are shown.

Figure 2: Stability of Roche Cell-Free DNA Collection Tube vs other competitors across different temperatures.

Samples collected and stored using the Roche Cell-Free DNA Collection Tube show comparable, if not better, stability at three different temperatures. Cell lysis metrics measured across 359 samples (Roche n=147, Competitor n=212) at 370°C, room temperature (RT), and 40°C are shown.

• >1 million tube usage worldwide
• Supported by best-in-class Roche service, logistics, and distribution network