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"Value": "CONFIRM anti-TTF-1 (8G7G3/1) antibody contains sufficient reagent for 50 tests.
One 5 mL dispenser of CONFIRM anti-TTF-1 (8G7G3/1) antibody contains approximately 35 μg of a purified mouse monoclonal antibody.
The antibody is diluted in Tris-HCI with carrier protein, and 0.10% ProClin 300, a preservative.
Specific antibody concentration is approximately 7 μg/mL.
There is no known non-specific antibody reactivity observed in this product.
CONFIRM anti-TTF-1 (8G7G3/1) antibodyis a purified monoclonal antibody produced as mouse ascites.
Refer to the appropriate VENTANA detection kit method sheet for detailed descriptions of: Principle of the Procedure, Material and Methods, Specimen Collection and Preparation for Analysis, Quality Control Procedures, Troubleshooting, Interpretation of Results, and Limitations.",
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This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and with proper controls.
This antibody is intended for in vitro diagnostic (IVD) use.",
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Tissue-specific exclusive expression of the thyroid gland and lung allows TTF-1 to be a useful marker for the classification of tumors arising in these organs.3 Detection of TTF-1 protein by immunohistochemistry (IHC) with the CONFIRM anti-Thyroid Transcription Factor-1 (8G7G3/1) Mouse Monoclonal Primary Antibody (CONFIRM anti-TTF-1 (8G7G3/1) antibody) may be used to aid in the classification of neoplasms of the thyroid and lung. It may be used as part of a panel in IHC studies.
1. Ordonez NG. Value of Thyroid Transcription Factor-1 Immunostaining in Tumor Diagnosis: A Review and Update. Appl Immunohistochem Mol Morphol. 2012;20(5):429-444.
2. Dabbs DJ. Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 5th Edition. 5th ed. Philadelphia, PA: Elsevier, 2019.
3. Tan D, Li Q, Deed G, et al. Thyroid transcription factor-1 expression prevalence and its clinical implications in non-small cell lung cancer: a high-throughput tissue microarray and immunohistochemistry study. Human Pathol. 2003;34:597-604.",
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Refer to the respective method sheets for further information.",
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