For in vitro diagnostic use. Nucleus Others VENTANA anti-PMS2 SP487 Rabbit Monoclonal Primary Antibody IVD Normal Colon VENTANA® anti-PMS2 (SP487) Rabbit Monoclonal Primary Antibody PID00001410 For use with VENTANA MMR IHC Panel Rabbit SP487 09 785 370 001 9 785 370 001 09785370001 9785370001 09785370001 VENTANA anti-PMS2 (SP487) PAB W VENTANA anti-PMS2 (SP487) PAB W 07613336220030 Reagents, kits 744-7186 50 tests Not Available undefined VENTANA anti-PMS2 (SP487) Rabbit Monoclonal Primary Antibody (VENTANA anti-PMS2 (SP487) antibody) is intended for the qualitative detection of PMS2 protein in formalinfixed, paraffin-embedded tissue sections. VENTANA anti-PMS2 (SP487) antibody is ready to use on BenchMark IHC/ISH instruments with the OptiView DAB IHC Detection Kit and ancillary reagents.VENTANA anti-PMS2 (SP487) antibody is part of the VENTANA MMR IHC Panel which includes VENTANA antiMLH1 (M1) Mouse Monoclonal Primary Antibody; VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody or VENTANA anti-PMS2 (SP487) Rabbit Monoclonal Primary Antibody; VENTANA anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody; VENTANA anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody; and VENTANA anti-BRAF V600E (VE1) Mouse Monoclonal Primary Antibody.The VENTANA MMR IHC Panel is indicated for the detection of mismatch repair protein deficiency as a test for the identification of individuals at risk for Lynch syndrome in patients diagnosed with colorectal cancer (CRC), and, with BRAF V600E status, as an aid to differentiate between sporadic and probable Lynch syndrome CRC in the absence of MLH1 protein expression.These products should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls.This antibody is intended for in vitro diagnostic (IVD) use. en VENTANA anti-PMS2 (SP487) antibody binds to PMS2 protein in formalin-fixed, paraffinembedded (FFPE) tissue sections. The antibody can be localized using a haptenated secondary antibody followed by a multimer anti-hapten-HRP conjugate (OptiView DAB IHC Detection Kit). The specific antibody-enzyme complex is then visualized with a precipitating enzyme reaction product. Each step is incubated for a precise time and temperature. At the end of each incubation step, each BenchMark IHC/ISH instrument washes the sections to stop the reaction and to remove unbound material that would hinder the desired reaction in subsequent steps. It also applies ULTRA LCS (Predilute) or LCS (Predilute), which minimizes evaporation of the aqueous reagents from the specimen slide. en

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VENTANA^® anti-PMS2 (SP487) Rabbit Monoclonal Primary Antibody

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