Dermatopathology IHC portfolio
Skin cancer is one of the most preventable cancers and highly treatable when found early
Reference: https://www.skincancer.org/skin-cancer-information/skin-cancer-facts/. Accessed 2/01/23.
Dermatopathology panel
Exceptional antibodies
Confidence and convenience
Pre-diluted, optimized antibodies come ready to use in dispensers that are specially designed for use on the VENTANA BenchMark IHC/ISH series of instruments. Ventana antibodies provide a convenient IHC solution for both routine and innovative diagnostic tests.
Fully automated, direct immunolfourescence staining
For autoimmune disorders and other inlfammatory processes Roche offers FITC- labeled antibodies against: C3, fibrinogen, IgA, IgG and IgM
Additional derm-related markers to meet a broad range of diagnostic needs including:
- Squamous cell vs. basal cell carcinoma
- Cutaneous lymphomas
- Dermatofibrosarcoma protuberans (DFSP)
- Merkel cell carcinoma
- Sebaceous carcinoma
Comprehensive melanoma panel
Melanoma is a malignancy of melanocytes and histology is the gold standard for distinguishing malignant cells from benigncells. IHC in this context is useful to establish melanocytic lineage (melanoma), versus other lineages (carcinoma, sarcoma, B- or T-cell lymphoma).
Contact Us
Featured Assays
SOX-10 (SP267) Rabbit Monoclonal Primary Antibody
SOX-10 (SP267) Rabbit Monoclonal Primary Antibody is intended for laboratory use in the detection of the SOX-10 protein in formalin-fxed, paraffin-embedded tissue stained on BenchMark immunohistochemical (IHC/ISH) automated slide stainers. SOX-10 is a nuclear transcription factor that participates in neural crest development and in the specification and differentiation of cells of melanocytic lineage.2
CONFIRM anti-MART-1/melan A (A103) Mouse Monoclonal Primary Antibody
CONFIRM anti-MART-1/melan A (A103) Mouse Monoclonal Primary Antibody is a mouse monoclonal antibody (IgG1) directed against melan A. Positive staining may aid in the classification of melanoma.2,3
Anti-PRAME (EPR20330) Rabbit Monoclonal Primary Antibody
The anti-PRAME (EPR20330) Rabbit Monoclonal Primary Antibody detects the overexpression of the tumor-associated antigen, PReferentially expressed Antigen in MElanoma (PRAME), in formalin-fixed paraffin embedded tissue. Positive staining may aid in the differentiation of benign versus malignant melanocytic lesions.4,5
Additional melanocytic markets
HMB45
Melanoma, with area showing normal melanocytes
CONFIRM anti-Melanosome (HMB45) Mouse Monoclonal Primary Antibody
Tyrosinase
Melanoma, with area showing normal melanocytes
CONFIRM anti-Tyrosinase (T311) Mouse Monoclonal Primary Antibody
Sensitive and specific detection systems
Roche offers ready-to-use detection systems in red and brown chromogens with the ability to perform dual chromogen staining that is compatible with any species combination of mouse and rabbit primary antibodies. The fexibility of our detection systems can help you achieve consistent, high-quality results to meet your IHC testing needs.
ultraView Universal Alkaline Phosphatase Red Detection Kit and ultraView Universal DAB Detection Kit
ultraView detection systems are leading-edge multimer-technology based kits
suitable for use with both mouse and rabbit primary antibodies
ultraView chemistry provides crisp morphology, enabling the sensitive and
specific visualisation of the targeted antigen. The kits are biotin-free, thus eliminating non-specific staining caused by endogenous biotin.
OptiView DAB IHC Detection Chemistry
By increasing the numbers of HRP enzymes at each primary antibody site,
OptiView DAB IHC detection provides unparalleled signal intensity, empowering
you to achieve the level of intensity you desire, even for low-expressing antigens.
Our synthetic, non-endogenous hapten system virtually eliminates background
even as signal intensity increases.
Flexible dual chromogen staining
Endless possibilities
- Greater context for diagnosis with brown and red chromogens
- Simpler, faster interpretation
- Compatible with any species combination of mouse and rabbit primary antibodies (mouse-mouse, rabbit-rabbit, rabbit-mouse)
Single stain — Dual stain — Single stain
PAX-5 (790-4420) and CD 3 (790-4341), tonsil 30x
Ki-67 (790-4286) and MART-1/melan- A (790-2990), skin 30x
CD45 (760-2505) and MART-1/melan-A (790-2990), skin 30x
BENCHMARK, CONFIRM, OPTIVIEW, ULTRAVIEW and VENTANA are trademarks of Roche.