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"IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "06-0057", "StructureGroupPath": "LifeScience->MagNA Pure LC 2.0 Accessories", "StructureGroupName": "MagNA Pure LC 2.0 Accessories", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "260", "StructureGroupPath": "MagNA Pure", "StructureGroupName": "MagNA Pure", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "010-00", "StructureGroupPath": "Molecular Lab", "StructureGroupName": "Molecular Lab", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "150-00", "StructureGroupPath": "Research Lab", "StructureGroupName": "Research Lab", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Product_Solutions", "NameofStructureSystem": "Product Solutions", "StructureNodeID": "100", "StructureGroupPath": "Molecular", "StructureGroupName": "Molecular", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "170-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Applications", "NameofStructureSystem": "Applications", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "OWP_Techniques", "NameofStructureSystem": "Techniques", "StructureNodeID": "999-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Disease_Areas", "NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" } ] }, { "ProductID": "3.8.2.4.3.1", "BrandName": "MagNA Pure Tip 1000μL", "ProductNameAddition": "", "ReferenceType": "Consumable", "Classification": [ { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "03-0703", "StructureGroupPath": "Molecular->MagNA Pure 96 Accessories and Consumables", "StructureGroupName": "MagNA Pure 96 Accessories and Consumables", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "260", "StructureGroupPath": "MagNA Pure", "StructureGroupName": "MagNA Pure", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "OWP_Product_Types", "NameofStructureSystem": "Product Types", "StructureNodeID": "50-000-00", "StructureGroupPath": "Consumables", "StructureGroupName": "Consumables", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "010-00", "StructureGroupPath": "Molecular Lab", "StructureGroupName": "Molecular Lab", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Product_Solutions", "NameofStructureSystem": "Product Solutions", "StructureNodeID": "100", "StructureGroupPath": "Molecular", "StructureGroupName": "Molecular", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "170-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Applications", "NameofStructureSystem": "Applications", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "OWP_Techniques", "NameofStructureSystem": "Techniques", "StructureNodeID": "999-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Disease_Areas", "NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" } ] }, { "ProductID": "3.8.11.3.4.1", "BrandName": "Tip CORE TIPS with Filter, 50uL", "ProductNameAddition": "", "ReferenceType": "Consumable", "Classification": [ { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "06-0006", "StructureGroupPath": "LifeScience->FLOW System Accessories and Disposables", "StructureGroupName": "FLOW System Accessories and Disposables", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "OWP_Product_Types", "NameofStructureSystem": "Product Types", "StructureNodeID": "50-000-00", "StructureGroupPath": "Consumables", "StructureGroupName": "Consumables", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "150-00", "StructureGroupPath": "Research Lab", "StructureGroupName": "Research Lab", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Product_Solutions", "NameofStructureSystem": "Product Solutions", "StructureNodeID": "100", "StructureGroupPath": "Molecular", "StructureGroupName": "Molecular", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "170-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Applications", "NameofStructureSystem": "Applications", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "OWP_Techniques", "NameofStructureSystem": "Techniques", "StructureNodeID": "999-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Disease_Areas", "NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "999", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" } ] } ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Name": "Intended Use", "Value": "Das MagNA Pure 24 System ist ein automatisches System zur Aufreinigung von Nukleinsäuren, das aus dem MagNA Pure 24 Instrument, der Software, Verbrauchsmaterialien und Reagenzien besteht. Das MagNA Pure 24 System ist für die Verwendung im professionellen Bereich ausgelegt und dient zur Aufreinigung von Nukleinsäuren aus Proben biologischen Ursprungs im Rahmen der In-vitro-Diagnostik.", "Language": "de", "Country": "XG", "Code": "Intended Use" }, { "Name": "Principle", "Value": "About run types and workflows

The MagNA Pure 24 System offers 4 run types:

Purification (rack) run
In a purification (rack) run, the instrument pipettes sample material from sample tubes, processes it, and transfers the eluates to the output consumables in the cooling station.
The purification (rack) run is the fully automated combination of a sample transfer run and a purification (cartridge) run.

Purification (cartridge) run
In a purification (cartridge) run, the processing cartridges are pre-filled with sample material, either in a previous sample transfer run, or by manual pipetting. The instrument processes the sample material, and transfers the eluates to the output consumables in the cooling station.
In the case of a previous sample transfer run, open the corresponding order to load sample details.

Post elution run
In a post elution run, the instrument pipettes eluates into 8-tube strips (either empty or containing manually prepipetted PCR master mix reagent). From each eluate, the instrument pipettes up to 2 eluate aliquots. Additionally, the instrument pipettes controls. Sample information from a previous purification run is loaded when reading the barcodes of the eluate output consumables.
A post elution run uses the cooling station only and requires a dedicated post elution adapter.

Sample transfer run
In a sample transfer run, the instrument pipettes sample material from sample tubes into processing cartridges.
You can then use the sample-filled processing cartridges in a purification (cartridge) run.

The run types differ in input and output and use different instrument stations.(see Fig. 2).
 
", "Language": "en", "Country": "XG", "Code": "Principle" }, { "Name": "Safety Information", "Value": "For safety related information refer to the MagNA Pure 24 Safety Manual.

Chemical reaction producing toxic gas
Mixing bleach or DNA AWAY™ Surface Decontaminant with reagents can result in a chemical reaction that produces a highly toxic gas.
-> Do not allow reagents containing guanidine thiocyanate to contact sodium hypochlorite (bleach) solution or acids.
See also the reference from the FDA: Transport Media Safety Risk - Use Compatible Transport Media with SARS-CoV-2 Tests that Use Bleach - Letter to Clinical Laboratory Staff and Health Care Providers.", "Language": "en", "Country": "XG", "Code": "Safety Information" }, { "Name": "Product Description", "Value": "The MagNA Pure 24 System is a fully automated clinical sample extractor. It extracts nucleic acids from various sample types, sample tubes, and volume inputs for multiple downstream applications.
The main features of the system are:

  • Scalable purification of 1 to 24 samples
  • Primary/secondary tube handling
  • Inventory and sample management via barcodes
  • Efficient order management via host
", "Language": "en", "Country": "XG", "Code": "Product Description" }, { "Name": "Content", "Value": "1. MagNA Pure 24 Instrument
2. Built-in control unit with preinstalled MagNA Pure 24 operating software and purification protocols
3. MagNA Pure 24 Accessories
4. Digital User Assistance", "Language": "en", "Country": "XG", "Code": "Content" } ] } } ] }

MagNA Pure 24 System

Beginnen Sie hier. Egal wo.

IVD For in vitro diagnostic use.
Produktbild für das MagNA Pure 24 System
Haben Sie Fragen?
KONTAKTIEREN SIE UNS
Mühelose Aufreinigung, Vertrauen durch Automatisierung
  • Bewährte Leistung für reproduzierbare und konstante Ergebnisse
  • Skalierbare Extraktion von 1-24 Proben mit Primärprobenhandhabung in etwas mehr als einer Stunde
  • Ein einziges universelles Reagenzkit für 10 humane Probentypen mit Volumeneingaben von 200 µL bis 4 ml
  • Vollständige Rückverfolgbarkeit mit Bestands- und Probenverfolgung über Barcodeüberwachung
  • Echte Walk-Away-Automatisierung
  • Kontaminationsschutz durch integrierte UV-Lampe und CO-RE Tip-Technologie

 

Vorgefülltes, mit Barcode versehenes und gebrauchsfertiges Reagenzkit

 

Das universelle MagNA Pure 24 Total Nukleinsäure-Kit eliminiert unnötige Komplexität und ermöglicht die effiziente Extraktion von Nukleinsäure aus 10 gängigen menschlichen Probentypen mit einem universellen Reagenzkit. Die Reagenzkassetten können für den späteren Gebrauch wiederverwendet werden, indem sie versiegelt werden, und das System kann die Verwendung der Reagenzien mit dem integrierten Barcode-Scanner identifizieren und nachverfolgen.

 

Die Flexibilität, mehr zu tun

 

Das MagNA Pure 24 System bietet Ihnen die Flexibilität, bis zu 10 verschiedene humane Probentypen mit einem einzigen universellen Reagenzkit zu extrahieren. Verlassen Sie sich auf dieses vereinfachte Reagenzienkonzept und wählen Sie eines der voroptimierten und vorprogrammierten Protokolle für die Extraktion aus gemischten Batch-Probentypen und Primärröhrchen innerhalb eines Protokolls.

Effizienz leicht gemacht

 

Das MagNA Pure 24 System ist nicht nur automatisiert. Es bietet einen echten Walk-Away-Betrieb mit einfacher Barcodeüberwachung und minimaler Benutzerinteraktion, sodass Sie menschliche Fehler reduzieren und wertvolle Zeit sparen können.

 

  • Einfache Einrichtung der Extraktion
  • Intuitive und geführte Benutzeroberfläche auf dem integrierten Touchscreen
  • Führen Sie das schnelle Protokoll für bis zu 8 Proben in 30 Minuten oder weniger aus
  • Weniger als 30 Sekunden Ladekontrolle vor einem Lauf
  • Schneller Gerätestart zu Beginn des Tages (<5 Minuten)
  • Nahtlose Daten-Verwaltung über LIS-Konnektivität
  • Vollautomatische Probenextraktion von FFPE-Gewebe mit Entparaffinisierung und Lyse im System

 

Eingebautes Vertrauen

 

Vertrauen in Ihr Eluat ist alles, wenn es um molekulares Testen geht. Das MagNA Pure 24 System ist ein IVD/CE-IVD-Instrument und verfügt über Überwachungsfunktionen, um die höchste Qualität von Eluat zu gewährleisten und gleichzeitig menschliche Fehler zu reduzieren.

 

  • Kontaminations- und Sicherheitskontrollfunktionen
  • Barcode-Funktion zur Verfolgung der Proben-ID und des Reagenzverbrauchs
  • Kühlstation zur Konservierung von Eluaten
  • Rückverfolgbare Software mit Audit-Management-Trail
  • Archivieren von Daten, die mit der Systemsoftware generiert wurden; Anzeigen von archivierten Daten mit dem eigenständigen Archive Viewer Archive Viewer auf Ihrem PC
  • Das Magna Pure 24 System ist derzeit auf der Softwareversion 1.2
Registrierungsstatus

IVD

Packungsbeilagen

Greifen Sie auf Packungsbeilagen über die Roche Diagnostics Website Ihres Landes zu.

Überblick

Bestellinformationen

Technische Dokumente

Zugriff auf die in Ihrem Land verfügbaren Dokumente

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Protokolle für das MagNA Pure 24 System

Die neuen MagNA Pure 24 System Protokollpakete 3.0 stehen in der nachstehenden Tabelle zum Herunterladen bereit (Hinweis: Download in den USA nicht verfügbar).

 

Erfolg
Formular erfolgreich abgesendet
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Target  Protocol name Input sample type and sample volumes
The latest version of MagNA Pure 24 protocols are available to download from the table below (not available in US)
 Elution volume  Run time♰ (h:mm)
 Whole blood  Plasma  Serum Nasal swabs*  BAL**
 Urine  Stool  Cultured cells Fresh-frozen tissue FFPET***
Bacterial, fungal and viral NA Pathogen 200  

Protocol optimized for speed

200 μL   50 or 100 μL 1:22
Fast Pathogen 200  

8 sample protocol optimized for speed, yield and purity

  0:35
Pathogen 1000

Protocol optimized for yield and purity

500 or 1000 μl   1:40
External Lysis Pathogen 200
External Lysis Pathogen 500  

Protocols optimized with external lysis buffer

450 μl lysate from 200 μl sample
1450 μl lysate from 500 μl sample
  1:30
1:40
Genomic DNA hgDNA 200  

Protocol optimized for human genomic NA

200 μl (≤ 2x106 cells)   Up to 5x105 Up to 5 mg   1:15
Fast hgDNA 200  

8 sample protocol optimized for speed

  0:25
hgDNA ds 200  

Protocol optimized for NGS

1:15
hgDNA 1000  

Protocol optimized for yield and purity

500 μl (≤ 5x106 cells)
1000 μl (≤ 1x107 cells)
100 or 200 μl 2:25
Up to 1x106
DNA FFPET 1000  

Deparaffinization and lysis on board

  Up to 6 x 5 μm sections (up to 6 mm3) 50 or 100 μl 5:30
Cell-free NA cfNA ss 2000
cfNA ss 4000  

Protocol optimized for single-stranded DNA

  2000 μL   50 or 100 μL 2:05
4000 μL 3:00
cfNA ds 2000
cfNA ds 4000  

Protocol optimized for double-stranded DNA

  2000 μL   100, 150 or 200 μL 2:30
4000 μL 3:30
cfNA ds 4000 hp  

Protocol optimized for double-stranded DNA and NGS

  4000 μL   60 or 150 μL 4:40
Post elution Sample Transfer   to the processing cartridge 200 μL
500 μL
1000 μL
  0.08
PCR Setup   for 2-25 μL per eluate for PCR Sstup in Frame-Strip with flat caps-Low Profile or LightCycler® 8-tube strips   0.05
Archiving   for 2-25 μL per eluate for PCR Sstup in FrameStrip low Profile strips or LightCycler® 8-tube strips 0.05
New Protocol
*Nasopharyngeal/nasal swabs
**BAL - Bronchoalveolar lavage
***FFPET - formalin-fixed paraffin-embedded tissue
♰These times are approximate and should only be used as a guidance.
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