For localized information and support, would you like to switch to your country-specific website for {0}?
KAPA HyperCap Custom Probes
Fully customizable panels for hybridization-based capture
Hybridization or capture-based target enrichment enables researchers to enrich specific target regions for next-generation sequencing (NGS).
Combining more than a decade of probe-design experience with an improved manufacturing process, Roche’s KAPA HyperCap target enrichment custom probes, together with the HyperDesign Tool for online custom target panel design, provide higher probe fidelity and improved hybridization-based capture target enrichment for NGS.
There are two types of KAPA HyperCap custom probes: KAPA HyperChoice Probes for human designs, and KAPA HyperExplore Probes for nonhuman designs.
Our custom portfolio of KAPA HyperChoice and KAPA HyperExplore probes, along with our other reagents and accessory products, helps scientists enhance their target enrichment workflow and save on sequencing costs.
Analytical performance of two KAPA HyperChoice designs
View full tableAnalytical performance of two KAPA HyperChoice designs
Design |
Neurodegenerative |
Hereditary disease |
Genes |
>98 |
> 4100 |
Target size (capture) |
335 Kb |
12.3 Mb |
HQ reads |
1.75 M |
20.00 M |
System |
NovaSeq 6000 |
NovaSeq 6000 |
% total duplicates |
2.78 |
1.62 |
Fold 80 (uniformity) |
1.38 |
1.43 |
% bases ≥30X |
99.83 |
97.22 |
Related products
HyperDesign Tool
HyperDesign Tool builds on two decades of in silico design experience to select probe panels that achieve deeper, more uniform downstream sequencing coverage with fewer sequencing reads—even across difficult-to-capture regions.
For Research Use Only. Not for use in diagnostic procedures.