cobas® 5800 System

Innovation made accessible

IVD For in vitro diagnostic use.
cobas® 5800 System
Confidently take on your lab’s changing needs

The cobas® 5800 System is a compact, fully automated molecular system that balances a broad menu and testing efficiency with flexible workflows and ease-of-use.

cobas® 5800 System introduction

cobas® 5800 System Overview


† Not all assays available. Some assays are in development, pending 510(K) clearance, or PMA approval.

‡ $16.1 billion USD invested in 2021.1


  1. Roche Annual Report 2021. Chairman's letter to shareholders. Available at: Accessed March 24, 2023.

End-to-end fully automated workflow for less hands-on time, more flexibility

The cobas® 5800 is the latest innovation in the x800 family of analyzers, cost-efficient solutions that combine to meet the changing demands for labs of all sizes.
cobas® 5800 hotspots

See specs for the cobas® 5800 System

The cobas® 5800 System supports an automated and integrated workflow to run Polymerase Chain Reaction (PCR) based Nucleic Acid Testing (NAT). Combining the functionalities of instrumentation, consumables, reagents, and data management provides an efficient workflow from sample processing to result interpretation.

Looking for additional cobas® 5800 product information?

Download these resources for answers to more specific questions. Or, fill out the contact form below and a Roche representative will set up a time to discuss details further. 

Our broad and expanding portfolio of assays is held to rigorous standards

Get accurate and actionable results for enabling better clinical decisions
Infectious Diseases
Sexual Health
  • CMV
  • EBV
  • BKV
  • ADV Quant (RUO) + ‡
  • HSV/VZV (RUO) + ‡

cobas omni Utility Channel for third-party tests and LDTs

‡ Research Use Only. Not for use in diagnostic procedures
+ In development for use with the cobas 5800.

Streamline your workflow using Roche innovation

Whether your lab is new to molecular testing, upgrading your equipment, or looking to expand output, you get big lab performance and small lab agility with scalable, cost-efficient solutions from Roche. Start here with the right products for your lab to develop a system that is scaled to your needs.

cobas® 8800 System

cobas 8800

Meet the growing needs of your lab with unparalleled automation, running up to 1,056 tests in an 8-hour shift. Only 3 user interactions per run for up to 4 hours of walk away time.

cobas® 6800 System

cobas 6800

Embrace the future of molecular testing with proven PCR performance. Learn about the cobas® 6800 System’s broad menu of high-quality assays, including HIV, HPV, CT/NG, Hepatitis, CMV, WNV, respiratory infections, and more.

cobas® prime System

cobas prime

The industry’s leading instruments converge to form a single solution that transforms your operation into a laboratory of the future. This fully automated system consolidates, integrates and standardizes the pre-analytical process to streamline lab operations.

Transforming testing and treatment together

Roche has been pioneering innovation in molecular testing for decades and remains committed to supporting laboratories in meeting both their own needs and the needs of the patients everywhere.

Speak with your Roche representative to learn more

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Ordering Information

Technical Documents


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Time to first results (up to 24 tests)* Subsequent runs (24 tests) • 2 hours 30 minutes
• Every 60 minutes thereafter
Maximum throughput (8 hrs | 24 hrs)* 144 | 528 tests
Walk-away time* Up to 8 hours
Test Format • Plates of up to 24 tests with up to 6 assays per plate
• Two 24 well thermal cyclers
User interactions • Load/unload samples, load reagents and consumables as needed
• Remove waste (solid and liquid)
• Review or auto-release results
Support for lab developed tests with the cobas omni utility channel • Develop and automate your own lab developed tests (LDTs) with up to 24 targets per plate
• Mixed processing of open channel assays** and Roche IVD assays
* May vary based on workflow demands.
** Open channel assays may include third-party assays, as well as routine lab-developed tests (LDTs).

Onboard inventory

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Onboard inventory

Sample capacity

• Up to 128 primary or secondary specimen tubes

• Up to 28 liquid based cytology vials (ThinPrep® PreservCyt Solution)

• Up to 80 samples loaded in 5-position racks

Reagent capacity Up to 15 (up to 7,200 tests)
Control mini racks Up to 16
cobas omni MGP reagent 1 (480 tests)
cobas omni specimen diluent reagent (1 L bottle)* 1 (240 tests)
cobas omni lysis reagent (1 L bottle) 2 (432 tests)
cobas omni wash reagent (4 L bottle)† 1 (240 tests)
cobas omni processing plates 24 4 (96 tests)
cobas omni liquid waste plates 24 4 (96 tests)
cobas omni amplification plates 24 8 (192 tests)
Processing tips‡ 3 x 96 (144 tests)
Eluate tips 2 x 96 (192 tests)
* Calculated for the addition of 350ul
† For 3-4 assays per run,
‡ 2 processing tips are needed per sample

Compatible tubes

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Compatible tubes

Tube dimensions acceptable for use on the cobas® 5800 System

Tube dimensions acceptable for use on the cobas® 5800 System

Tube size Acceptable measurement (mm)
Height 65–103
Outside diameter (includes barcode label) 12–16.2

Barcode types supported

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Barcode types supported

1D barcodes:
  • Code 128
  • Code 39
  • Codabar
  • Interleaved 2 of 5
  • EAN-8
  • EAN-13
  • Code 93
2D barcodes:
  • Data matrix ECC 200
  • Aztec code

Power supply

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Power supply

Line voltage

100-240 VAC 
+/- 10%

Line frequency 50/60Hz +/- 5%
Maximum power consumption 1600 VA

Dimensions and weight

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Dimensions and weight

Instrument dimensions

53 x 73 x 32 inches
(W x H x D)

Instrument weight 

1374 lbs.

X800 Data Manager

  • Functions as a central server when interconnecting and operating multiple systems
  • System connectivity: up to 3 analytic systems managed by a single x800 Data Manager
  • LIS Connectivity: uni- and bi-directional communication using HL7 standard protocol
  • Order/ Result Handling
  • User Management
  • Configurations for user, assay priority, etc
  • Can be accessed via web browser on laboratory PC

Contamination prevention

  • Airlock doors
  • Pipette tips with CO-RE filter technology
  • Single use consumables
  • Dedicated pipette tips for each sample transfer and for transfer of extracted nucleic acid
  • Stainless steel pipettes transfer assay-specific reagents, bulk reagent dispensing - washed after each use
  • Controls (RMCs) transferred with pipette tips
  • Automatic heat sealing of cobas omni Amplification Plate
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