Next-generation sequencing assays for precision oncology research
Deliver critical oncology insights with our portfolio of NGS assays
Precision oncology aims to personalize cancer treatment by identifying targetable alterations in a tumor. Next-generation sequencing (NGS) enables the accurate interrogation of large numbers of genes in parallel, thereby providing the comprehensive information necessary to inform decisions regarding targeted therapies. As the need for precision oncology expands, NGS assays will become an indispensable tool in clinical oncology research, delivering more insights more quickly.1
Our broad portfolio of innovative NGS assays for oncology research is designed to help you and your laboratory achieve your objectives. AVENIO NGS Oncology Assay kits offer in-house tumor profiling, comprehensive genomic profiling (CGP), as well as surveillance and monitoring.2
Versatile NGS assay portfolio with integrated end-to-end workflows
AVENIO NGS Oncology Assay kits provide researchers with a versatile solution for tumor tissue and ctDNA analysis with an integrated end-to-end research workflow.
Whether you require the detection of ultra-low quantities of ctDNA, or work with challenging formalin-fixed paraffin-embedded (FFPE) tissue samples, AVENIO NGS Oncology Assays offer accurate and reliable in-house tumor profiling, comprehensive genomic profiling (CGP), and surveillance & monitoring.2
AVENIO NGS Oncology Assay kits include all of the reagents for DNA extraction, sample input QC (tissue only), library preparation, and target enrichment; as well as robust bioinformatics and secondary analysis (variant analysis)—all from a single, trusted source. The highly efficient workflow has been optimized to minimize hands-on time and deliver high-quality results in just five days—making it easy for you to obtain reliable genomic insights in your lab.2
Shaping the future of oncology: NGS assays that can inspire clinical breakthroughs
Treating cancer demands a personalized approach, relying on high-quality assays, validated bioinformatics pipelines and workflows, and the relentless pursuit to provide patients with better healthcare outcomes.
Roche has developed a broad portfolio of NGS assay solutions based on extensive expertise in oncology and diagnostics, which informs high-quality research.
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Leverage the depth and breadth of next-generation sequencing for precision oncology research.
Benefits of NGS assays from Roche
Versatile portfolio of NGS assays to suit your research needs
AVENIO NGS Oncology Assay kits provide researchers with a versatile solution for tumor tissue and ctDNA analysis.
- Accurate and reliable detection and analysis of ultra-low quantities of ctDNA, as well as robust analysis of challenging formalin-fixed paraffin-embedded (FFPE) tissue samples2
- In-house tumor profiling, comprehensive genomic profiling (CGP), and surveillance and monitoring2
- Comprehensive Genomic Profiling (CGP) Kits with a 335-gene panel aligned with the FoundationOne® CDx panel design. These kits enable detection of four classes of genomic variants (single nucleotide variants, insertions/deletions, copy number variants, and rearrangements/fusions), and complex genomic signatures such as Tumor Mutational Burden (TMB), Microsatellite Instability (MSI), genomic Loss of Heterozygosity (gLOH), as well as the newly added Homologous Recombination Deficiency signature (HRDsig)3,4
Fully integrated, optimized end-to-end workflow
AVENIO NGS Oncology Assays are designed to make it easy for you to obtain reliable genomic tumor insights in your lab.
- Matched tissue and ctDNA panels (same genes, gene regions, and hybrid-capture workflow) for true concordance2
- All four mutation classes (SNVs, indels, fusions, and CNVs) in a single DNA workflow2
- Streamlined, end-to-end research workflow optimized to minimize hands-on time and deliver high-quality results (DNA extraction to analysis and reporting) in just five days2
- Integrated solutions that include reagents, intuitive analysis, and variant reporting—to facilitate in-house adoption of high-performance NGS assays for oncology research2
Robust performance from your trusted partners in oncology research
AVENIO NGS assays were rigorously optimized using thousands of samples.
- As a result, AVENIO assays deliver the exceptional performance you expect from Roche and Foundation Medicine, diagnostic leaders and your trusted partners in oncology research3,4
- Leveraging the FoundationOne® Analysis Platform for bioinformatics and secondary analysis, and the AVENIO workflows, the AVENIO Tumor Tissue CGP kits are part of Roche’s broad portfolio that offers flexible CGP solutions and support services to meet your research needs3,4
- AVENIO NGS Oncology Assays produce extremely high levels of sensitivity and specificity for the detection of SNVs, indels, fusions, and CNVs2
*CGP is available for tissue only.
AVENIO products are for Research Use Only. Not for use in diagnostic procedures.
References
- Morash M, et al. The Role of Next-Generation Sequencing in Precision Medicine: A Review of Outcomes in Oncology. J Pers Med. 2018 Sep;8(3):30.
- F. Hoffmann-La Roche. Data on file.
- AVENIO Tumor Tissue CGP Automated Kit IFU v2.0. May 2025.
- F. Hoffmann- La Roche. AVENIO Tumor Tissue CGP Kit V2 Instructions for Use. (v3.0). December 2025.