LightCycler® PRO System

Light the way from research to clinical diagnostics with the next evolution in the Roche qPCR portfolio
IVD For in vitro diagnostic use.
LightCycler® PRO System

A qPCR system designed to deliver accuracy and flexibility to research and clinical diagnostic laboratories

The LightCycler® PRO system combines the functionalities of instrumentation, consumables, reagents, and data management to support a semi-automated workflow for polymerase chain reaction-based nucleic acid testing.1

Leveraging the robustness and proven technology of the LightCycler® 480,* the LightCycler® PRO integrates innovative technology and Roche manufacturing to deliver accurate real-time PCR results and an improved user experience for your lab.

Increase your lab’s testing capabilities

TIB Molbiol provides a comprehensive assay menu for both research and clinical diagnostic uses.** This includes the LightMix® Modular Assay Kits, which are meticulously tailored for optimal performance on the LightCycler® PRO system, ensuring user-friendly convenience without compromising result quality, reliability, or reproducibility.

LightCycler Pro System
Benefits at a glance

Benefits at a glance

Have confidence in the accuracy of your results

  • Patented Vapor Chamber Mount design delivers precise temperature regulation and enhanced sensitivity
  • Optical module design for uniform excitation, edge effect prevention, simultaneous data capture, and flexible dye options and detection formats
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Adapt quickly to your lab’s evolving testing needs

  • New seven-channel multiplexing increases hourly throughput and enables greater diversity of tests per run
  • Thermal Cycler with interchangeable 96- or 384-well plates offers variable throughput options to support your lab’s specific needs
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Streamline workflow efficiency with easy data management options

  • Large, 40 cm touchscreen improves user interface and enables easy access to workflow and data management options
  • Easy import/export of data, LIS connectivity, and remote access
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Related categories

Related information

Meet the newest addition to the Roche real-time PCR portfolio

Explore the newest qPCR analyzer for your lab's research and clinical diagnostic needs

lightcycler pro expanded
Improved algorithms deliver reliable data you can depend on

The new LightCycler® PRO software optimizes existing algorithms to improve functionality, performance, and precise data analysis.2

These new enhancements include:

  • A new adaptive algorithm which improves color compensation across the 7 channels to prevent crosstalk and contaminated results. This algorithm is optimized for use with LightMix® modular assays.
  • An updated derivative algorithm which automatically determines the Cq value from the PCR run data for confidence in results calling.
TIB Molbiol LightMix Modular Gastro Bacteria 7-target multiplexed assay

TIB Molbiol LightMix® Modular Gastro Bacteria 7-target multiplexed assay – optimized to detect 7 different targets from a single well

TIB Molbiol LightMix Modular Gastro Bacteria 7-target multiplexed assay

LightCycler® PRO System, dilution series 10^1 to 10^8 copies, demonstrating high precision and accuracy.

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Product specification 

Value

General characteristics 

Automation 

  • Automatic run/start when loading a valid plate and existing plate setup

  • HL7-based host interface to a customer LIS (Laboratory Information System)

  • Barcode-assisted scanning of multi-well plates

Remote monitoring 

Remote access to host computer for process monitoring and reviewing data

Data management 

Compatibility with 21 CFR Part 11

Interfaces 

  • 6 x USB 2.0 on the back of the device

  • 2 x USB 2.0 on the front of the device

  • 1 x HDMI for external display on the back of the device

  • 1 x Ethernet port on the back of the device

Temperature control 

Peltier-based heating/cooling from 20°C-99°C

Integrated vapor chamber for optimal temperature distribution

Heating rate 

96-well-block: 4.4 °C/s

384-well-block: 4.8 °C/s

Filter 

7 Excitation

7 Emission

Detector 

CMOS Camera

Light source 

White LED lamp

Dimensions and weight 

Instrument dimensions 

45.3 x 54.3 x 50.4 cm (W x H x D)

Instrument weight 

54.5 kg

Power supply 

Voltage 

100-240 VAC

Line frequency 

50/60 Hz

Technical Documents

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    Contact us

    Do you have questions about this product or service? We’re here to help. Fill out the form to contact a Roche representative.

    *For research use only. Not for use in diagnostic procedures.

    **Some assays are only available through TIB Molbiol or Roche. Assay availability varies by country. Contact your local representative for more information.

    References

    1. F. Hoffmann-La Roche Ltd. LightCycler® PRO System SW1.2 User Guide 2.0. (v2.0). 2025.
    2. F. Hoffmann-La Roche Ltd. V&V Report: DH-02714.04-500B. Data on file.