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For Research Use Only. Not for use in diagnostic procedures. Others KAPA HyperExome V2 Probes RUO KAPA HyperExome V2 Probes PID00000515 Superior uniformity and low duplication
Reduced sequencing costs
Renowned probe design and selection algorithm
Achieve broad database coverage in an efficient compact design
More uniform coverage across the GC % range
Confidence in variants calling
High precision (99.49%) and recall (98.95%) for SNP detection
Intrinsically targeted sample tracking SNPs eliminate the need to spike-in external controls
Optimized with the KAPA HyperCap Workflow v3.4
Streamlined and easily automatable enables high sample throughput
en The KAPA HyperExome V2 Probes deliver exceptional coverage of the recent versions of ACMGv3.1, RefSeq (June 29, 2022), CCDS, ClinVar (June 29, 2022), Ensembl v106 and COSMIC genomic databases across 20626 genes within a compact capture target of 43.2 Mb and with low sequencing requirements. The new T2T (telomere-to-telomere) genome assembly was utilized as part of the design process to identify potentially problematic regions not apparent in the GRCh38 genome assembly. The number of sample tracking SNPs has increased to 529. en