Article

The emerging role of comprehensive genomic profiling in cancer care

Published on March 3, 2025 | 5 min read
The emerging role of comprehensive genomic profiling in cancer care

References

  1. MedStar Health. (2023). Article available from https://www.medstarhealth.org/blog/cancer-treatment-advances#:~:text=Advances%20in%20cancer%20treatment%20in,and%20there's%20more%20to%20come [Accessed January 2025]
  2. World Health Organization. (2024). Article available from https://www.who.int/news/item/01-02-2024-global-cancer-burden-growing--amidst-mounting-need-for-services [Accessed January 2025]
  3. European Society for Medical Oncology. (2023) Article available from https://www.esmo.org/oncology-news/estimate-of-the-global-economic-cost-of-the-most-prevalent-cancers-in-204-countries-from-2020-to-2050 [Accessed January 2025]
  4. F. Hoffman-La Roche Ltd. (2025). Article available from https://www.roche.com/stories/genomic-profiling-in-personalised-healthcare [Accessed January 2025]
  5. Schwab M, editor. (2008). Encyclopedia of Cancer. New York: Springer
  6. Stratton MR et al. (2009). Nature. 458, 719-724. Paper available from https://www.nature.com/articles/nature07943 [Accessed January 2025]
  7. Strachan T et al. (2015). New Insights from Genomewide Studies of Cancers. In: Genetics and Genomics in Medicine. New York and London: Garland Science
  8. Krzysczyk P et al. (2019). Technology. 6(3-4), 79-100. Paper available from https://pmc.ncbi.nlm.nih.gov/articles/PMC6352312/ [Accessed January 2025]
  9. BioSpace. (2024). Article available from https://www.biospace.com/oncology-drugs-market-to-reach-usd-532-91-billion-by-2031-coherent-market-insights [Accessed January 2025]
  10. Schrock AB et al. (2016). Clin Cancer Res. 22(13):3281-5. Paper available from https://pubmed.ncbi.nlm.nih.gov/26933124/ [Accessed January 2025]
  11. breastcancer.org. (2022). Article available from https://www.breastcancer.org/screening-testing/molecular-profiling [Accessed January 2025]
  12. Drilon A et al. (2015). Clin Cancer Res. 21(16), 3631-3639.  Paper available from https://aacrjournals.org/clincancerres/article/21/16/3631/117318/Broad-Hybrid-Capture-Based-Next-Generation [Accessed January 2025]
  13. Rozenblum AB et al. (2017). J Thorac Oncol. 12(2), 258-268. Paper available from  https://pubmed.ncbi.nlm.nih.gov/27865871/ [Accessed January 2025]
  14. Johnston KM et al. (2020). Curr Oncol. 27(6), e569-e577. Paper available from https://pubmed.ncbi.nlm.nih.gov/33380872/ [Accessed January 2025]
  15. Harvey MJ et al. (2021). JCO Precis Oncol. 5, 1611-1624. Paper available from https://pubmed.ncbi.nlm.nih.gov/34994647/ [Accessed January 2025]
  16. Perdrizet K et al. (2022). Cancer Treat Res Commun. 31, 100534.  Paper available from https://pubmed.ncbi.nlm.nih.gov/35278845/ [Accessed January 2025]
  17. Dalal AA et al. (2018). Journal of Medical Economics. 21(7), 649-655. Paper available from https://www.tandfonline.com/doi/full/10.1080/13696998.2018.1450261 [Accessed January 2025]
  18. Singal G et al. (2019). JAMA. 321(14), 1391-1399. Paper available from https://jamanetwork.com/journals/jama/fullarticle/2730114 [Accessed January 2025]
  19. Singh AP et al. (2020). Cancers (Basel). 12(5), 1156. Paper available from https://pubmed.ncbi.nlm.nih.gov/32375398/ [Accessed January 2025]
  20. Freedman AN et al. (2018). JCO Precis Oncol. 2, 1-13. Paper available from https://ascopubs.org/doi/10.1200/PO.18.00169 [Accessed January 2025]
  21. Vears DF et al. (2017). Eur J Med Genet. 60(10), 553-558. Paper available from  https://pubmed.ncbi.nlm.nih.gov/28774848/ [Accessed January 2025]
  22. Yaung SJ and Pek A. (2021). J Mol Pathol. 2(4), 312-318. Paper available from https://www.mdpi.com/2673-5261/2/4/27 [Accessed January 2025]
  23. seqWell. (2023). Article available from https://seqwell.com/in-house-ngs-vs-outsourced-sequencing-services-which-option-makes-the-most-sense-for-your-lab/ [Accessed January 2025]
  24. Hayashi H et al. (2020). Cancer Sci. 111(10), 3926-3937. Paper available from https://pmc.ncbi.nlm.nih.gov/articles/PMC7540994/ [Accessed January 2025]

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