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"Value": "CD38 molecule is a 46-kDa type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail (20 amino acids) and a long extracellular domain (256 amino acids). CD38 is expressed at low or moderate levels on various hematopoietic cells and in some solid tissues.
1-3 CD38 is one of the early markers of mature naive B-cell activation and it is useful in classifying functional mature B-lymphocyte subsets.
1-31. Martin F et al. Marginal-zone B cells. Nat Rev Immunol. 2002; 2:323-35.
2. Dono M, et al. Heterogeneity of tonsillar subepithelial B lymphocytes, the splenic marginal zone equivalents. J Immunol. 2000; 164:5596-5604.
3. Malavasi F, et al. Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology. Physiol Rev. 2008; 88:841-86.",
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