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6-12References
- Anderson JM, Van Itallie CM. Physiology and Function of the Tight Junction. Cold Spring Harbor Perspectives in Biology. 2009;1(2):a002584
- Martin TA. The role of tight junctions in cancer metastasis. Semin Cell Dev Biol. 2014;36:224-31.
- Gunzel D, Yu AS. Claudins and the modulation of tight junction permeability. Physiol Rev. 2013;93:525-69.
- Tsukita S, Furuse M, Itoh M. Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol. 2001;2:285-93.
- Niimi T, Nagashima K, Ward JM, et al. Claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing. Mol Cell Biol.
2001;21:7380-90. - Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. Clin Cancer Res. 2008;14:7624-34.
- Tureci O, Koslowski M, Helftenbein G, et al. Claudin-18 gene structure, regulation, and expression is evolutionary conserved in mammals. Gene. 2011;481:83-92.
- Woll S, Schlitter AM, Dhaene K, et al. Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms. Int J Cancer. 2014;134:731-9.
- Karanjawala ZE, Illei PB, Ashfaq R, et al. New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. Am J Surg Pathol. 2008;32:188-96.
- Shinozaki A, Shibahara J, Noda N, et al. Claudin-18 in biliary neoplasms. Its significance in the classification of intrahepatic cholangiocarcinoma. Virchows Arch. 2011;459:73-80.
- Tanaka M, Shibahara J, Fukushima N, et al. Claudin-18 is an early-stage marker of pancreatic carcinogenesis. J Histochem Cytochem. 2011;59:942-52.
- Micke P, Mattsson JS, Edlund K, et al. Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer. Int J Cancer.
2014;135:2206-14. - Carson F, Hladik C. Histotechnology: A Self Instructional Text, 3rd edition. Hong Kong: American Society for Clinical Pathology Press; 2009.
- Roche PC, Hsi ED. Immunohistochemistry-Principles and Advances. Manual of Clinical Laboratory Immunology, 6th edition. In: NR Rose, ed. ASM Press; 2002.
- Merikallio H, Pääkkö P, Harju T, Soini Y.. Claudins 10 and 18 are Predominantly Expressed in Lung Adenocarcinomas and in Tumors of Nonsmokers. Int J Clin Exp Pathol. 4(7):667-673. 2011.
- Sanada Y, Oue N, Mitani Y et al. Down-regulation of the Claudin-18 Gene, Identified through Serial Analysis of Gene Expression Data Analysis, in Gastric Cancer with an Intestinal Phenotype. J Pathol. 208:633-642. 2006.
- Economou M., Schoni L, Hammer C et al. Proper paraffin slide storage is crucial for translational research projects involving immunohistochemistry Clin Transl Med 2014:3:4. Published online 2014 Mar 17.
- Xie R, Chung JY, Ylaya K, et al. Factors influencing the degradation of archival formalin-fixed paraffin-embedded tissue sections. J Histochem Cytochem. 2011;3:356–365.
- Bertheau P, Cazals-Hatem D, Meignin V, et al. Variability of immunohistochemical reactivity on stored paraffin slides. J Clin Pathol. 1998;3:370–374.
- Ramos-Vara JA, Webster JD, Dusold D, Miller MA. Immunohistochemical evaluation of the effects of paraffin section storage on biomarker stability. Vet Pathol. 2014;3:102–109.
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},
{
"Name": "Product Purpose",
"Value": "VENTANA CLDN18 (43-14A) Assay est conçu pour la détection immunohistochimique de la protéine claudine 18 (CLDN18) dans des tissus néoplasiques fixés au formol et inclus en paraffine (FFPE) colorés à l’aide d’instruments BenchMark IHC/ISH. Ce produit doit être interprété par un anatomopathologiste qualifié, en conjonction avec un examen histologique, les informations cliniques pertinentes et des contrôles appropriés.
Cet anticorps est conçu pour être utilisé dans le cadre du diagnostic
in vitro (IVD).",
"Language": "fr",
"Country": "XG",
"Code": "Product Purpose"
}
]
}
}
]
}