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Do not freeze.", "Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Intended Use", "Value": "L’anticorps Epstein-Barr Virus (CS1-4) Mouse Monoclonal Primary Antibody est destiné à l’usage en laboratoire pour la détection du virus d’Epstein-Barr dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur des instruments IHC/ISH VENTANA BenchMark. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic in vitro (IVD).", "Language": "fr", "Country": "XG", "Code": "Intended Use" }, { "Name": "Background Information", "Value": "Anti-Epstein-Barr virus targets the 60 kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the Epstein-Barr virus. There is cross-reactivity with Reed-Sternberg cells of Hodgkin disease. The Epstein-Barr virus is an important cause of infectious mononucleosis and has been associated with oral carcinomas.1-4

1. Murray PG, et al. Immunohistochemical demonstration of the Epstein-Barr virus-encoded latent membrane protein in paraffin sections of Hodgkin’s disease. J Pathol. 1992; 166:1-5.
2. Jarrett RF, et al. Detection of Epstein-Barr virus genomes in Hodgkin’s disease: relation to age. J Clin Pathol. 1991; 44:844-8.
3. Pallesen G, et al. Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin’s disease. Lancet. 1991; 337:320-2.
4. Silverberg GS, et al. Principles and Practice of Surgical Pathology and Cytopathology, 3rd edition. 1997.", "Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Content", "Value": "One dispenser of this antibody contains sufficient prediluted reagent for 50 tests.", "Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Principle", "Value": "Epstein Barr Virus (CS1-4) Mouse Monoclonal Antibody (this antibody) may be used as the primary antibody for immunohistochemical staining of formalin-fixed, paraffin-embedded tissue sections. In general, immunohistochemical staining allows the visualization of antigens via the sequential application of a specific antibody (primary antibody) to the antigen, a secondary antibody (link antibody) to the primary antibody, an enzyme complex and a chromogenic substrate with interposed washing steps. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and a coverslip applied. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen.

This antibody is optimally diluted to be compatible with VENTANA detection kits and BenchMark IHC/ISH instruments. Refer to the Tables in the Instructions for Use section for recommended staining protocols. Each step in the staining protocol includes incubation for a precise time at a specific temperature. At the end of each incubation step, the sections are rinsed by the BenchMark IHC/ISH instruments to stop the reaction and remove unbound material that would hinder the desired reaction in subsequent steps. To minimize evaporation of the aqueous reagents from the specimen-containing slide, a coverslip solution is applied in the slide stainer. For more detailed information on instrument operation, refer to the appropriate BenchMark IHC/ISH instruments Operator’s Manual.", "Language": "en", "Country": "XG", "Code": "Principle" }, { "Name": "Product Purpose", "Value": "L’anticorps Epstein-Barr Virus (CS1-4) Mouse Monoclonal Primary Antibody est destiné à l’usage en laboratoire pour la détection du virus d’Epstein-Barr dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur des instruments IHC/ISH VENTANA BenchMark. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic in vitro (IVD).", "Language": "fr", "Country": "XG", "Code": "Product Purpose" } ] } } ] }

Epstein-Barr Virus (CS1-4) Mouse Monoclonal Antibody

IVD For in vitro diagnostic use.
Epstein-Barr Virus (CS1-4) Mouse Monoclonal Antibody

Description

Detailed Specifications

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