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Do not freeze.", "Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Background Information", "Value": "Human growth hormone (GH) is a single-chain polypeptide containing 191 amino acid residues with two disulfide bridges.¹ GH participates in a wide range of biological functions such as metabolism of proteins, carbohydrates and lipids and is also involved with growth, development and immunity.¹ GH is synthesized in acidophilic cells of the anterior pituitary gland by a subpopulation of cells with the somatotroph phenotype.² Anti-GH is a useful marker in the classification of pituitary tumors and can be used in the study of pituitary disease.^2-4

1. Rezaei, Marzieh, and Syyed H. Zarkesh-Esfahani. “Optimization of Production of Recombinant Human Growth Hormone in Escherichia Coli.” Journal of Research in Medical Sciences: The Official Journal of Isfahan Univerisity of Medical Sciences. 2012; 17.7:681-5.
2. Al-Brahim NY, et al. My Approach to Pathology of the Pituitary Gland. J Clin Pathol. 2006; 59:1245-53.
3. Fukaya T, et al. Morphofunctional study of pituitary adenomas with acromegaly by immunoperoxidase technique and electron microscopy. Cancer. 1980; 45:1598-1603.
4. Kovacs K, et al. Adenoma of the human pituitary producing growth hormone and thyrotropin. A histologic, immunocytologic and fine-structural study. Virch Arch Pathol Anat. 1982; 395:59-68.", "Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Intended Use", "Value": "L’anticorps primaire polyclonal de lapin de la GH (hormone de croissance) est destiné à l’usage en laboratoire pour la détection de l’hormone de croissance dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur les instruments (IHC/ISH) BenchMark de VENTANA. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic in vitro (IVD).", "Language": "fr", "Country": "XG", "Code": "Intended Use" }, { "Name": "Content", "Value": "One dispenser of this antibody contains sufficient prediluted reagent for 50 tests.", "Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Principle", "Value": "GH (Growth Hormone) Rabbit Polyclonal Antibody (this antibody) may be used as the\nprimary antibody for immunohistochemical staining of formalin-fixed, paraffin-embedded\ntissue sections. In general, immunohistochemical staining allows the visualization of antigens\nvia the sequential application of a specific antibody (primary antibody) to the antigen, a\nsecondary antibody (link antibody) to the primary antibody, an enzyme complex and a\nchromogenic substrate with interposed washing steps. The enzymatic activation of the\nchromogen results in a visible reaction product at the antigen site. The specimen may then be\ncounterstained and a coverslip applied. Results are interpreted using a light microscope and\naid in the differential diagnosis of pathophysiological processes, which may or may not be\nassociated with a particular antigen.\n
\n
\nThis antibody is optimally diluted to be compatible with VENTANA detection kits and\nBenchMark IHC/ISH instruments. Refer to the Tables in the Instructions for Use section for\nrecommended staining protocols. Each step in the staining protocol includes incubation for\na precise time at a specific temperature. At the end of each incubation step, the sections are\nrinsed by the BenchMark IHC/ISH instruments to stop the reaction and remove unbound\nmaterial that would hinder the desired reaction in subsequent steps. To minimize evaporation\nof the aqueous reagents from the specimen-containing slide, a coverslip solution is applied\nin the slide stainer. For more detailed information on instrument operation, refer to the\nappropriate BenchMark IHC/ISH instruments Operator’s Manual.", "Language": "en", "Country": "XG", "Code": "Principle" }, { "Name": "Product Purpose", "Value": "L’anticorps primaire polyclonal de lapin de la GH (hormone de croissance) est destiné à l’usage en laboratoire pour la détection de l’hormone de croissance dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur les instruments (IHC/ISH) BenchMark de VENTANA. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic in vitro (IVD).", "Language": "fr", "Country": "XG", "Code": "Product Purpose" } ] } } ] }