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"Value": "Anti-MUC1 (H23) contains sufficient reagent for 50 tests.
One 5 mL dispenser of anti-MUC1 (H23) antibody contains approximately 50 μg of a mouse monoclonal antibody.
The antibody is diluted in phosphate buffered saline with 0.10% ProClin 300, a preservative.
Specific antibody concentration is approximately 10 μg/mL. There is no known non-specific antibody reactivity observed in this product.
Anti-MUC1 (H23) antibody is a mouse monoclonal antibody produced as cell culture supernatant.
Refer to the appropriate VENTANA detection kit method sheet for detailed descriptions of: Principle of the Procedure, Material and Methods, Specimen Collection and Preparation for Analysis, Quality Control Procedures, Troubleshooting, Interpretation of Results, and Limitations.",
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1. Lau SK, Weiss LM, Chu PG. Differential Expression of MUC1, MUC2, and MUC5ac in Carcinomas of Various Sites: An Immunohistochemical Study. Am J Clin Pathol. 2004;122(1):61-69.
2. Lopez-Ferrer A, Curull V, Barranco C, et al. Mucins as Differentiation Markers in Bronchial Epithelium. Squamous Cell Carcinoma and Adenocarcinoma Display Similar Expression Patterns. Am J Respir Cell Mol Biol. 2001;24(1):22-29.
3. Pinkus GS, Kurtin PJ. Epithelial Membrane Antigen--a Diagnostic Discriminant in Surgical Pathology: Immunohistochemical Profile in Epithelial, Mesenchymal, and Hematopoietic Neoplasms Using Paraffin Sections and Monoclonal Antibodies. Hum Pathol. 1985;16(9):929-940.
4. Sloane JP, Ormerod MG. Distribution of Epithelial Membrane Antigen in Normal and Neoplastic Tissues and It Value in Diagnostic Tumor Pathology. Cancer. 1981;47(7):1786-1795.
5. Collado Martin R, Garcia Palomo A, de la Cruz Merino L, et al. Clinical Guideline SEOM: Cancer of Unknown Primary Site. Clin Transl Oncol. 2014;16(12):1091-1097.
6. Massard C, Loriot Y, Fizazi K. Carcinomas of an Unknown Primary Origin--Diagnosis and Treatment. Nat Rev Clin Oncol. 2011;8(12):701-710.
7. Lin F, Liu H. Immunohistochemistry in Undifferentiated Neoplasm/Tumor of Uncertain Origin. Arch Pathol Lab Med. 2014;138(12):1583-1610.",
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