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"ProductSpec": [
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"Chapters": [
{
"Name": "Storage Conditions (Product)",
"Value": "Upon receipt and when not in use, store at 2-8°C. Do not freeze.",
"Language": "en",
"Country": "XG",
"Code": "Storage Conditions (Product)"
},
{
"Name": "Content",
"Value": "One dispenser of this antibody contains sufficient prediluted reagent for 50 tests.",
"Language": "en",
"Country": "XG",
"Code": "Content"
},
{
"Name": "Intended Use",
"Value": "L’anticorps primaire polyclonal de lapin de la prolactine est destiné à l’usage en laboratoire pour la détection de la protéine prolactine dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur les instruments (IHC/ISH) BenchMark de VENTANA. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic
in vitro (IVD).",
"Language": "fr",
"Country": "XG",
"Code": "Intended Use"
},
{
"Name": "Background Information",
"Value": "Prolactin (PRL) is a single-chain polypeptide of 226 amino acids and plays a role in multiple processes including cell growth, reproduction, and immune function. Anti-Prolactin reacts with prolactin-producing cells and is a useful marker in classification of pituitary tumors and the study of pituitary disease.
1-51. Asa SL, et al. Prolactin cells in the human pituitary. A quantitative immunocytochemical analysis. Arch Pathol Lab Med. 1982; 106:360-3.
2. Duello TM, et al. Immunocytochemistry of prolactin-producing human pituitary adenomas. Am J Anat. 1980; 158:463-9.
3. Minniti G, et al. Giant prolactinomas presenting as skull base tumors. Surg Neurol. 2002; 57:99-103.
4. Popadic A, et al. Malignant prolactinoma: case report and review of the literature. Surg Neurol. 1999; 51:47-54.
5. Nevalainen MT, et al. Prolactin and prolactin receptors are expressed and functioning in human prostate. J Clin Invest. 1997; 99:618-27.",
"Language": "en",
"Country": "XG",
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},
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"Value": "Prolactin Rabbit Polyclonal Antibody (this antibody) may be used as the primary antibody\nfor immunohistochemical staining of formalin-fixed, paraffin-embedded tissue sections. In\ngeneral, immunohistochemical staining allows the visualization of antigens via the sequential\napplication of a specific antibody (primary antibody) to the antigen, a secondary antibody\n(link antibody) to the primary antibody, an enzyme complex and a chromogenic substrate\nwith interposed washing steps. The enzymatic activation of the chromogen results in a visible\nreaction product at the antigen site. The specimen may then be counterstained and a coverslip\napplied. Results are interpreted using a light microscope and aid in the differential diagnosis\nof pathophysiological processes, which may or may not be associated with a particular\nantigen.\n
\n
\nThis antibody is optimally diluted to be compatible with VENTANA detection kits and\nBenchMark IHC/ISH instruments. Refer to the Tables in the Instructions for Use section for\nrecommended staining protocols. Each step in the staining protocol includes incubation for\na precise time at a specific temperature. At the end of each incubation step, the sections are\nrinsed by the BenchMark IHC/ISH instruments to stop the reaction and remove unbound\nmaterial that would hinder the desired reaction in subsequent steps. To minimize evaporation\nof the aqueous reagents from the specimen-containing slide, a coverslip solution is applied\nin the slide stainer. For more detailed information on instrument operation, refer to the\nappropriate BenchMark IHC/ISH instruments Operator’s Manual.",
"Language": "en",
"Country": "XG",
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"Value": "L’anticorps primaire polyclonal de lapin de la prolactine est destiné à l’usage en laboratoire pour la détection de la protéine prolactine dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur les instruments (IHC/ISH) BenchMark de VENTANA. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic
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